LATAM Airlines Group (together with their partners) offer discounted return flights from Rome to Sao Paulo. For very limited travel dates you can book roundtrip flights on said route already for €337 incl. all taxes and fees and onboard meals. Checked bag available for extra fee. Flights have one layover in Frankfurt or Madrid on your way. In some cases (also as per our booking sample) you may find solution with a non-stop flight (inbound leg).
As mentioned LATAM AIrlines offer very limited availability at the lowest fare. Look for flights in travel period from 9th of January till 14th of May 2019. Based on latest date of your outbound flight from Italy to Brazil. Below you can find our booking as well as few travel date samples. You can compare all the cheapest flights Rome-Sao Paulo directly at website of the carrier.
Booking sample
Rome - Sao Paulo from €337
Travel samples
9. - 24.1.
25.1. - 7.2.
27.1. - 9.2.
2. - 15.2.
9. - 23.2.
16.2. - 3.3.
2. - 17.3.
13. - 26.3.
7. - 18.5.
8. - 21.5.
9. - 23.5.
14. - 27.5.
Need affordable hotel in Brazil book your accommodation via Booking.com or Hotels.com. If you have booked these cheap flights from Rome to Sao Paulo you can also compare best prices for car rental in this destination via Rentalcars.com.
Booking sample of cheap flights from Rome to Sao Paulo from €337 return here. In htis case you would depart from Italy to Brazil on 9th of May. Return from South America back to Europe (direct service) on 22nd of May 2019.